Topic outline

  • BAB 1206: BASIC BIOCHEMISTRY

    Basic biochemistry module is designed to equip the learner with knowledge, skills and attitude to enable them to develop a good understanding of nutrition, conduct their research project, participate in nutrition and health related studies.

    The prerequisite modules include; Human anatomy and physiology, Principles of human nutrition, and physical sciences.  The module takes 60 contact hours: 37 hours for theory and 23 hours for practical. Learners undertaking this module will have both theory and practical assessments. Formative assessment will be in the form of continuous assessment tests, assignments, clinical and field assessments and promotional examination whereas summative assessment will be done in form of final qualifying examination.
  • a)  Introduction
    Proteins are polymers of amino acids joined together by peptide bonds. They can be distinguished from fats and carbohydrates by containing nitrogen. Other components include carbon, hydrogen, oxygen, Sulphur, and sometimes phosphorus. The type and the sequence of amino acids in a protein are specified by the DNA. The sequence of amino acids is important since it determines the overall structure and function of a protein. Proteins are required for the structure, function, and regulation of the body's cells, tissues, and organs; and each protein has unique functions



    b) Unit Objectives

    By the end of this unit, you shall be able to;

    1. Understand the classification of amino acids
    2. Explain the structures of proteins
    3. Explain the denaturation of proteins
    4. Explain the metabolism of proteins
    5. Explain the classification of proteins and their functions


    c) Unit Learning Requirements
    To proficiently complete this unit, you ought to make sure you spend quality time and purpose to;

      1. Carry out all tasks within the sections and subsections
      2. Participate in discussion forums as and when they are scheduled.
      3. Participate in chat sessions as and when they are scheduled.
      Learning requirements

      • View Go through the activity to the end
      • Describe the functions of proteins

        2. Explain obligatory nitrogen loss from the body and how it relates to amino acid requirement.

        3. Discuss protein classification and give examples

        4. Draw and explain the formation of a peptide bond.

        5. Discuss the methods used to determine protein quality

        6. How does the body eliminate excess nitrogen?

        7.  Define negative nitrogen balance. What factors contribute to it?

        8.  Explain transamination reactions in protein metabolism.

        9.  What is the function of urea cycle?

        10.  Explain factors that increase Blood urea nitrogen.

        11.  Explain three ways in which amino acid ‘carbon skeletons” are utilized in energy production

        12.  List two hormones involved in protein metabolism.

        13.  Explain phenylketonuria (PKU).

        14.   Explain why the urea cycle enzymes increase during acute starvation